Diagnosis of Tubal Intraepithelial Lesions

Pathologists from the Johns Hopkins Medical Institutions, University of Toronto, Yale University and Memorial Sloan Kettering Cancer Center have created the diagnostic criteria and algorithm¬†(see below)¬†to standardize the diagnosis of various fallopian tube lesions that may represent the precursor lesions of “ovarian” high-grade serous carcinomas. Please click the subpages (Definition and Algorithm, Images of Training Set, and Testing Cases) to start viewing the contents if you agree with the following statement:

The intention of the information provided in this web site is at present for educational and research purposes only. The biological and clinical significance of STIC and STIL is a work in progress and their impact to clinical management has still to be defined. The investigators involved in this study and all the web pages in ovariancancerprevention.org do not recommend the use of this pathological and immunostaining classification for clinical practice at the present time.